I have one large old file (200GB) among many small ones in a folder being uploaded to Dropbox Backup.
However, the upload appears to be continually restarting, even though no software on the computer should be touching the file for any kind of write.
I've left my computer running with updates disabled for three days straight so far so that the file could try to back up. The farthest it has gotten is less than 10 GB.
After leaving it go for a while, I can open the Dropbox window again from the notification area icon to check the progress, and it will have restarted the upload over again, showing 199.8 GB remaining and back down to 166 GB out of 366 GB backed up.
This file is never going to back up, and I don't know why.